The efficacy of therapeutic molecules is often limited by the insufficient delivery, accumulation in target tissues or undesirable side effects even severe toxicities in healthy organs. Liposomes are round bubbles consisting of an aqueous core encapsulated by natural or synthetic phospholipids. The success of Doxil (liposomal doxorubicin) is due to the reduced cardiac toxicity compared to free drugs. Other nanoformulations such as Abraxane (albumin paclitaxel) have improved the solubility of the drug.
We can prepare your targeted drug inside the core of liposome to increase the efficacy and reduce the toxicity avoiding preclinical and clinical expensive common problems.
